Experts in container rentals, sales and customization. | Let us help you today! 800.686.9114
Southwest Mobile Storage is a family-owned shipping container business founded in 1995. Our strength for more than 25 years comes from the specialized knowledge and passion of our people, along with serving over 24,000 commercial, construction and residential customers. Our facility and expertise in maintaining, manufacturing, and delivering corrugated steel containers is unrivaled in the industry.
While the rental side of our business is regional with branches throughout the Southwest, our container sales and modification operations are nationwide and becoming global. Encino, CA offers a wide selection of portable offices and mobile storage containers you can rent, buy or modify.
Our experts in container rental, sales and customization are committed to providing you the highest quality and best experience from service to delivery - our reputation depends on it.
Whether your need is for storage, office space, moving, multi-purpose or custom use, we've got your back. Here's how:
We bring your storage container to you for convenient, easy access at your home, business or jobsite. Plus, you'll get more choice in storage space and better security, for a fraction of the cost of a pod or add on building, saving money and energy.
Not enough room to keep a storage container at your business, home or construction site? No problem - we can store it for you. Plus, you get 70% more space and better security, for a fraction of the cost of public storage units.
Need a permanent storage solution for your business, residence or construction? We sell new and used shipping containers in many sizes with a variety of add-ons. Or customize a container to your specific storage needs with our certified fabrication experts.
Take your time packing with our moving containers. We'll deliver to your business or home and pick it up whenever you're ready to move. So, you don't have to stress about moving or making multiple trips in one day, like if you rented a moving truck.
Our moving container solutions ensure the long-distance move of your home or business is highly efficient and affordable throughout the southwest. In fact, we usually cost 20%-40% less than full-service movers.
We understand move-in and move-out dates might be different. We can store your moving container at our highly secure facilities until you're ready to move to your new home or business location, and you can conveniently access it at any time.
Whether you need a workspace, conference room, or other office requirement, our ground-mounted mobile offices meet any and all of your business needs. Plus, it's faster and easier than building additions.
If you need your shipping container to serve multiple uses, such as office-storage combos, breakrooms and even utilities, we've got you covered. We'll modify a custom container to fit your business needs and bring your business to the next level
We'll create a custom container to fit your unique needs anywhere in the US. With our container modification expertise, we make any idea a reality. From pop-up stores to multi-story structures, our unrivaled facilities and fabrication experts do it all.
With Southwest Mobile Storage, you get much more than a POD or typical Conex box. You also get high security, unparalleled service and unmatched container modification expertise and facilities. No other company offers that much.
Shipping containers and storage containers come in a range of sizes. The most common external lengths are 20ft and 40ft with a width of 8ft. ISO Containers are typically 8ft 6in tall, but high cube containers are 9ft 6in tall. We also have steel containers in a variety of sizes from 10ft long to 45ft long to rent or buy, and we can modify shipping containers into any size you want.
Having flexible storage containers options is important, but security is crucial to protect your peace of mind and your possessions.
At Southwest Mobile Storage, we don't believe in leaving things to chance. We want you to rest easy knowing your inventory, documents, tools, equipment and other items are safe 24/7. That is why we equip SMS high-security slide bolt locking systems and lockboxes on our entire fleet of rental freight containers.
Contact us to speak with a helpful, friendly representative to better understand our full range of capabilities. We are happy to answer any questions you have, go over pricing and set up a time and place to deliver your Conex box. Our quotes are 100% free and you are under no obligation to pay for your consultation.
When you own a business or manage one, it's crucial to have efficient, affordable ways to store inventory and supplies, whether it's to grow your business or adapt to changes in the market, like the many caused by the pandemic.
Renting storage containers to keep at your business eliminates the cost and hassles of sending your staff to offsite storage facilities. Steel containers with roll up doors make storing and retrieving items faster and easier. Auto repair shops and other businesses that need easy access throughout the workday to secure storage for tools, parts, equipment or supplies find renting shipping containers to be the best solution for their business storage needs. Southwest Mobile Storage has your back.
Renting portable offices gives your business more workspace, breakrooms, pop up stores, security booths and more, without the cost and red tape associated with constructing building additions. Plus, a steel storage container fits neatly into one parking space and provides much stronger security than Pods and way more convenience than self-storage units.
If you have a specific need, we can modify shipping containers to build whatever you need to grow your business. Whether it's a portable workspace to run your business, like a pop-up container bar, or a durable facility for scientific research, like a container laboratory, or even a container gym, our unrivaled fabrication facility and modification experts got you covered. Our full-time, in-house staff of certified welders, engineers, electricians, carpenters and painters have over 500 years combined experience modifying thousands of container projects for just about any business use you can imagine.
Building additions to your home can be very expensive and requires going through the hassle of securing permits and waiting for construction. You can save money, time and stress by modifying a shipping container instead. Whether you need additional space for a home gym, recreation or storage, we can convert steel containers into anything you can imagine. Our custom container gyms, man-caves or she-sheds, garages and more give you the extra space you need without the hassle, cost and wait that comes with home renovation.
Renting shipping containers for temporary storage, either when moving or dealing with restoration from a fire or flood, provides a secure, convenient way to keep your belongings close for accessing them whenever you need to. Plus, renting mobile storage containers for moving costs less than traditional movers and allows you to take your time packing, reducing the stress that comes from moving. You can also rent portable offices for your home to make working remotely distraction-free.
With an extensive in-house staff and 90,000 sq ft container modification facility, we're able to deliver consistently high quality and work on multiple projects simultaneously for a fast turnaround.
Other companies don't have the facility, staff or resources to modify shipping containers and will outsource the work to various shops who may not have the special experience or tools needed to modify the right way.
You can rest assured knowing your custom container is safe in our hands. Our certified weld and quality control inspectors ensure everything is structurally sound and built to your specifications through every step of the process.
Renting a moving container from us makes your move much less stressful because you won't have to rush to pack your whole house into a moving truck in one day. Instead, you can take your time packing over the course of a month.
Our ISO shipping containers are weatherproof and come with vault-like security, so you don't have to worry about theft or damage to your belongings.
You won't get that level of security from U-Haul or other moving truck companies.
Renting a storage container at your home keeps your belongings close and gives you convenient 24/7 access, so you're always able to retrieve the contents of your container when you need to.
We know move in and move out dates don't always line up. We can store your packed rental container at our secure facility until your new home is ready.
With our mobile storage containers for rent in Encino, CA, you can save up to 40% when compared to full-service long-distance movers, while gaining more flexibility in your schedule.
We know your needs may change suddenly. With our extensive inventory and variety of sizes of portable offices and shipping containers to rent, buy or modify in Encino, CA, we provide fast service and the best value possible so it's easy for you to get whatever you need when you need it.
Renting storage containers and portable offices from us gives you more flexibility when it comes to your schedule and options. If you don't have enough space at your current location or simply would prefer offsite storage, you can keep your rental storage and office containers at your location or ours - whichever is most convenient for you. You also get more options to choose from when it comes to size and features, like portable offices with divided rooms for private meetings or office/storage combos for storage and office space in one container. All while costing a fraction of the price of a pod or self-storage facility.
-Rivian 40' Office Delivery R1
- Office Storage Combo for Rent
- Office 2017-7 R1
- Monitoring Station 1 R1
- Custom Communications Tower M R1
You can also buy new or used freight containers from us and choose from a variety of add-ons, including lights, electricity, doors and windows. Or fully customize a shipping container to save time, money and energy by skipping the expensive, lengthy process of constructing building additions. We can modify a Conex box into whatever you can imagine for any use you need, from construction tool cribs to office buildings, monitoring stations, mobile communication towers and much more. The possibilities are endless.
You'll never face hidden fees or surprises with us. We give you transparent billing up front at the best prices.
With us, you get a reliable, dedicated point of contact, who keeps you updated every step of the way. You can rest assured knowing you'll always get what you need, when you need it.
No other company has the breadth and depth of staff and experience that we do when it comes to modifying shipping containers. Our certified welders, engineers, electricians, plumbers, carpenters and painters have more than 500 years of combined experience in fabricating custom steel containers.
We prorate your rent by the day after the first 28-day billing cycle, so you don't have to pay for a full month when you only have your mobile containers and offices for a few days.
While other companies may be able to do small container modifications, most don't have an in-house fabrication staff or 90,000 sq ft fabrication facility like we do. As a result, they outsource the work on your custom container, so you don't know who's actually building it.
Rest assured knowing your modified shipping container will be built to the highest quality standards. Our certified weld and quality control inspectors check every step of the fabrication process to ensure everything is structurally sound and built to your specifications.
Whether you're in need of a storage container for your commercial business, a portable office for your construction site, or a moving container for your home, our process is simple and straightforward.
Choose the mobile storage solution that works best for your needs. In this step, you will let us know the number of containers you need, their sizes and what types of doors to equip.
Let us know if you would like to add any of our rental options, like a folding table or shelving.
Choose from padlocks, puck locks and other enhanced security options. All of our storage containers come standard with dual-locking, vault-like security.
You can expect standard delivery within 3-5 days of your order. If you need expedited delivery, we will do everything in our power to accommodate your needs.
Do you need to keep your shipping container at our location? Prefer to have our team deliver your packed container to a location of your choice? Let us know, and we'll be by your side to work out the logistics.
Let our team know where we should deliver your mobile storage container for rent in Encino, CA. Be sure to let us know if there are any special conditions that might prevent our drivers from entering your chosen destination. Before you schedule your delivery, let us know which direction you would like the doors of your container to face.
Our drivers can deliver your storage container Monday-Friday, between the hours of 6AM and 2PM local time. Our two-hour delivery window is the most precise in the industry. If you desire another delivery time outside of our standard delivery options, we will do our best to accommodate your needs. As a courtesy, our driver will call you at least 30 minutes before they arrive at your drop-off destination.
Before we deliver your Conex box, prepare your delivery area by ensuring that there are no low overhangs, arches, wires, trees or any other obstacles that could interfere with your delivery. It's a good idea to mark the space where you would like your steel container placed.
When our driver arrives, they will back our truck into the space where you would like your shipping container placed. Once we arrive, we will ensure that your container is delivered safely and securely. If placed on asphalt or pavement, we will use wood dunnage pads to make sure your ground surface is protected and the container is level.
Check out our FAQ page or reach out to our helpful customer service team today @
909.341.4736In 2011 he founded The Agency, which the Netflix show focuses onNetflix has just released Buying Beverly Hills, another reality show all about the most luxurious real estate in LA. This one focuses on a brokerage run by Mauricio Umansky, which has helped him to earn himself a pretty eye-watering net worth.Mauricio Umansky owns The Agency in Beverly Hills, California. Mauricio, his daughters Farra...
In 2011 he founded The Agency, which the Netflix show focuses on
Netflix has just released Buying Beverly Hills, another reality show all about the most luxurious real estate in LA. This one focuses on a brokerage run by Mauricio Umansky, which has helped him to earn himself a pretty eye-watering net worth.
Mauricio Umansky owns The Agency in Beverly Hills, California. Mauricio, his daughters Farrah and Alexia, and the talented group of agents highlight the high stakes world of luxury real estate in Los Angeles. From shows like Selling Sunset we’ve learned that real estate makes people mega bucks, so just how rich is Mauricio Umansky?
Mauricio is known as one of the most successful realtors in the country, and in the series we see the company has listings priced at $42million and $139million in its books at the moment. Casually. He’s also married to Kyle Richards, and has appeared on The Real Housewives of Beverly Hills alongside her before.
His career actually began in fashion, after graduating Mauricio founded a clothing company called 90265. The company did well, and he was able to successfully sell it when he was aged 26. He founded real estate company The Agency in 2011 and has had some pretty impressive celebrity clients, such as the Hemsworth brothers.
Right now, Mauricio Umansky is said to be sitting on a net worth of $100million. His brokerage is said to sell more than $150million worth of property every year on average. His wife Kyle is also mega rich. She’s one of the richest cast members in the Real Housewives of Beverly Hills, also worth $100million. So between them, they have a joint net worth of $200million.
Mauricio and Kyle own some pretty impressive real estate assets of their own. They’ve lived in a huge home in Encino, California since 2017 and also have a holiday home in the desert in La Quinta, California.
Buying Beverly Hills is available on Netflix now. For all the latest Netflix news, drops, quizzes and memes like The Holy Church of Netflix on Facebook.
• Selling Sunset cast net worths: Here’s just how filthy rich they all actually are
• Selling Sunset transformations: What the cast looked like before they got rich and famous
• So, Alexa from Love Is Blind’s family lives in a $2.4m home and her dad owns a nightclub
Bleacher Report catches you up on the latest news from the WWE Universe.WWE Reportedly Tried to Keep Theory's Cash-In a SurpriseAustin Theory cashing in his Money in the Bank contract on Monday night's episode of Raw was reportedly kept under wraps by WWE going into the show.According to Fightful Select (h/t WrestlingInc's ...
Bleacher Report catches you up on the latest news from the WWE Universe.
WWE Reportedly Tried to Keep Theory's Cash-In a Surprise
Austin Theory cashing in his Money in the Bank contract on Monday night's episode of Raw was reportedly kept under wraps by WWE going into the show.
According to Fightful Select (h/t WrestlingInc's Fernando Quiles Jr.), Theory's cash-in was not listed on internal documents, making it the only thing that occurred on Raw that wasn't on the run sheet.
Theory's cash-in was indeed shocking since he used his contract on Seth Rollins' United States Championship rather than Roman Reigns' undisputed Universal Championship, marking the first time Money in the Bank wasn't used on a world title.
On top of that, Theory lost after Bobby Lashley interfered in the match, making him one of just a handful of Superstars to cash in the briefcase and lose.
Theory won Money in the Bank when Vince McMahon was head of WWE creative, and it was clear that he was on the fast track to becoming a top star and future world champion.
There were questions regarding whether Theory's standing would change when McMahon retired and Triple H took over as head of creative in July, and that does seem to be the case.
Triple H was chiefly responsible for signing Theory and building him up in NXT, though, which could mean The Game still sees big things for him in the future.
For now, the unsuccessful cash-in on the United States Championship means he will essentially have to be rebuilt from the ground up.
Major Spots Planned for Survivor Series WarGames?
Performers are reportedly expected to pull off some wild spots in the men's and women's WarGames matches at Survivor Series WarGames this month.
According to Bryan Alvarez of Wrestling Observer Radio (h/t Sunil Joseph of Ringside News), there is likely to be some "craziness" in the WarGames matches so WWE can use the footage for promotion of future WarGames matches and premium live events.
Alvarez noted that WWE's desire for that type of footage stems from the fact that many of the Superstars who took part in WarGames matches in NXT are no longer with the company.
Undisputed Era competed in four of the five men's WarGames matches in NXT, and the only member of that group still under contract with WWE is Roderick Strong.
Other NXT WarGames participants gone from WWE include AOP, Sanity, Keith Lee, Oney Lorcan, Danny Burch, Tegan Nox, Toni Storm and Ember Moon.
Every wrestler from both WarGames matches at last year's event is still with WWE, however.
Regardless of any need for footage, WarGames matches are conducive to huge spots and memorable moments, and there is little doubt that the men's and women's WarGames matches at Survivor Series will have all of that in spades.
The women's match will pit Damage CTRL, Nikki Cross and a partner to be named against Bianca Belair, Asuka and Alexa Bliss and two unknown teammates. No announcements have been made on the men's WarGames match, but it figures to feature The Bloodline on one side.
Bringing WarGames to the main roster was one of Triple H's first major announcements after becoming head of creative, so he will likely do everything in his power to ensure it succeeds.
Paul Already Rehabbing Knee Injury
Just days after suffering a knee injury at Crown Jewel in Saudi Arabia, Logan Paul is already on the road to recovery.
According to Subhojeet Mukherjee of Ringside News, Paul posted video of himself rehabbing at Sports Rehab LA in Encino, California, on his Instagram story.
Last week Saturday, Paul competed in the main event of Crown Jewel, falling to undisputed WWE universal champion Roman Reigns in a match that was widely praised.
After the match, Paul announced that he suffered a torn meniscus and MCL, as well as a potentially torn ACL.
If Paul did indeed tear multiple knee ligaments, including his ACL, it is likely that he will miss at least six months, and perhaps even as much as a year depending on how his recovery goes.
Paul is a part-time wrestler, so he may not have been scheduled for many matches during that time, but it seems likely that he would have been part of WrestleMania.
That almost certainly won't be possible if Paul tore his ACL, meaning WWE could be without some major star power.
Wrestling fans were seemingly hesitant to embrace Paul at first, but given how well he has performed in just three career matches, fans seem to be coming around.
The Crown Jewel match established Paul as a threat near the top of the card, and he is likely to be involved in something huge whenever he returns from injury.
Listen to Ring Rust Radio for all of the hot wrestling topics. Catch the latest episode in the player below (warning: some language NSFW).
Vanessa Hudgens and Paris Jackson led stars down the red carpet at Prince Jackson's Thriller Night Halloween party in Encino, Cali...
Vanessa Hudgens and Paris Jackson led stars down the red carpet at Prince Jackson's Thriller Night Halloween party in Encino, California on Friday night.
Channeling the Black Swan, Hudgens wowed in a plunging gown covered in black feathers that highlighted her ample chest.
Several feathery strands cascaded down onto the train of the dress that pooled around the High School Musical alum as she posed for shutterbugs.
Star-studded: Vanessa Hudgens and Paris Jackson led stars down the red carpet at Prince Jackson's Thriller Night Halloween party in Encino, California on Friday night
Her toned legs and platform black patent leather boots peeked out through a daring thigh-high slit.
For some added drama, Hudgens rocked bold black eyeshadow blended in the shape of bird wings. Her lips were painted a glossy black and her cheeks were dusted with shimmery bronzer for a radiant appearance.
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Proving to be a huge fan of the Lord Of The Rings franchise, Jackson, 24, was dressed as on the the Black Riders -- mortal men who were turned into evil servants of Sauron.
The daughter of Michael Jackson modeled a black cloak which she layered over a black slip skirt and bra.
She had the creepy craw-like gloves and spiked helmets donned by the five ominous figures in the beloved fantasy films.
Haley Reinhart put on a leggy display in a tiny white dress which clung tightly to her curves.
Black Swan: Channeling the Black Swan, Hudgens wowed in a plunging gown covered in black feathers that highlighted her ample chest
Dramatic: Several feathery strands cascaded down onto the train of the dress that pooled around the High School Musical alum as she posed for shutterbugs
The 32-year-old added a bright orange wig which ended in soft curls in the middle of her back. The bangs of the wig ended in the middle of her forehead.
She finished off her spot-on Wilma Flintstone with white earrings, a white necklace and matching high heel shoes.
Her lips were painted a cherry red which matched her sharp nails.
Transformation: Proving to be a huge fan of the Lord Of The Rings franchise, Jackson, 24, was dressed as on the the Black Riders -- mortal men who were turned into evil servants of Sauron
The daughter of Michael Jackson modeled a black cloak which she layered over a black slip skirt and bra. She had the creepy craw-like gloves and spiked helmets donned by the five ominous figures in the beloved fantasy films
She went as part of a pair's costume with Drew Dolan who dressed up in a Fred Flintstone onesie, left partially unzipped to the middle of his chest.
Alexandra Shipp left little to the imagination with a huge set of beads covering her chest and bright orange skirt.
The skirt was slit down the right side, showing off her tanned leg and intricate tattoos. Her raven-colored hair fell into a bob which ended just above her slender shoulders.
Perfect: The 32-year-old added a bright orange wig which ended in soft curls in the middle of her back. The bangs of the wig ended in the middle of her forehead
White accessories: She finished off her spot-on Wilma Flintstone with white earrings, necklace and matching high heel shoes
Dynamic duo: She went as part of a pair's costume with Drew Dolan who dressed up in a Fred Flintstone onesie, left partially unzipped to the middle of his chest
David Granados attended the event in a classic costume, an all leather suit reminiscent to Michael Jackson's costume in the Thriller music video.
He wore a black shirt underneath the leather jacket and a pair of shiny black shoes.
Jordin Sparks wore a blue Hawaiian shirt over a sleeveless orange top, and she added an auburn-colored wig to the outfit as well.
The 32-year-old singer wore light blue denim jeans and bedazzled black boots. She carried a tiny plush monkey with her as well.
Leggy: The skirt was slit down the right side, showing off her tanned leg and intricate tattoos. Her raven-colored hair fell into a bob which ended just above her slender shoulders
Thriller! David Granados attended the event in a classic costume, an all leather suit reminiscent to Michael Jackson's costume in the Thriller music video
Anna DeGuzman bared some skin in a black sweater which she left open to her navel, revealing her black bra underneath.
She added comfy-looking black pants and feather black sandals. The star wore a black bowler with a piece of white paper sticking out of the lip.
She carried a magic wand and a dazzling silver and gold purse in her hand as well. She flashed a brilliant white smile and her lips were painted a vibrant pink.
Casual: Jordin Sparks wore a blue Hawaiian shirt over a sleeveless orange top, and she added an auburn-colored wig to the outfit as well
Comfy black outfit: Anna DeGuzman bared some skin in a black sweater which she left open to her navel, revealing her black bra underneath
Prince Michael Jackson looked ready to jump on some mushrooms and save some princesses in a classic Mario costume.
The 20-year-old was joined at the party, which he hosted, by his longtime love Molly Schirmang who donned a pink Princess Peach outfit with a huge silver crown.
Zuri Hall looked angelic in a white toga with a thin strap wrapped around her right shoulder. The gold rope tied around her waist perfectly matched the headband and hoop earrings.
Here we go! Prince Michael Jackson looked ready to jump on some mushrooms and save some princesses in a classic Mario costume
Couple: The 20-year-old was joined at the party, which he hosted, by his longtime love Molly Schirmang
Family: Prince was later spotted alongside several other stars including his brother Blanket Jackson
Broadway star: They were joined by actor Myles Frost who starred as Michael Jackson in the Broadway show MJ the Musical (left)
Prince was later spotted alongside several other stars including his brother Blanket Jackson, who dressed simply in a black hoodie and matching baseball cap.
They were joined by actor Myles Frost who starred as their father Michael in the Broadway show MJ the Musical.
Frost dressed as the Black Panther complete with a mask and a fake six pack of abs.
Prince also stood next to Rush Hour star Chris Tucker who stunned in an all black suit. Singer-songwriter Tevin Campbell wore a white suit and pants with gorgeous floral designs running all over it.
Toga, toga! Zuri Hall looked angelic in a white toga with a thin strap wrapped around her right shoulder
Comic books: Tara Strong showed off her natural curves in a form-fitting Harley Quinn outfit. The black and red patterned ensemble came with huge black combat boots (pictured left with with Willie Morris, right)
Tara Strong showed off her natural curves in a form-fitting Harley Quinn outfit. The black and red patterned ensemble came with huge black combat boots.
Her platinum blonde hair was tied up in the back, and thick strands of it fell to her jaw. The 49-year-old's costume was complimented by Willie Morris who dressed as Heath Ledger's Joker from The Dark Knight.
Thriller Night is an annual party hosted by the Jackson family, named after Michael Jackson's popular Halloween track.
Different men have different needs when it comes to metastatic PC—which often point the way to the right treatment approach, doctors say.Metastatic prostate cancer can feel like a pretty scary diagnosis. It means that the disease has spread beyond your prostate to other parts of your body, such as your lymph nodes, bones, liver, and lungs. Unlike the disease in its early stages, prostate cancer at this point cannot be cured. B...
Metastatic prostate cancer can feel like a pretty scary diagnosis. It means that the disease has spread beyond your prostate to other parts of your body, such as your lymph nodes, bones, liver, and lungs. Unlike the disease in its early stages, prostate cancer at this point cannot be cured. But that doesn’t mean there’s no hope—there is. New approaches to treatment have shown to significantly prolong lives while maintaining quality of life. Let’s take a look at how cancer specialists view mono-, doublet, and triplet therapies—and which one might be best for you.
Prostate cancer is fueled by androgens (male sex hormones), the most abundant of which is testosterone. Most androgens are produced in your testicles, though your adrenal glands and even cancer cells can produce small amounts, too. To slow the disease, doctors perform castration—we know that sounds bad, but keep reading—to stop androgen production. They do so with hormone therapy, using medications or, less commonly, the surgical removal of your testicles. “The backbone of treatment is androgen suppression,” says Manish A. Vira, M.D., the system chief of urology at the Northwell Cancer Institute in New Hyde Park, NY.
Hormone therapy is most effective in men who are considered what cancer specialists call ‘”hormone-sensitive,” responding well to either medical or surgical castration. As the disease progresses, however, hormone therapy becomes less and less effective for most men. This stage is known as “castrate-resistant” prostate cancer, and it is much harder to treat. “[Castration-resistant prostate cancer] is a very difficult space,” says Sandy Liu, M.D., medical director of genitourinary medical oncology at City of Hope Orange County in Irvine, CA. A primary goal of hormone therapy is to keep the cancer from progressing to that point for as long as possible.
Hormone therapy most often involves a cocktail of different treatments. It usually includes two drugs, called a doublet, though the latest research has shown that a three-drug combination, or triplet therapy, has significantly greater benefits. Rarely, doctors use a single drug strategy, called monotherapy, for men with advanced prostate cancer because combination therapy typically works better. “People live longer” with combination therapy, says John Shen, M.D., a medical oncologist at UCLA Health Encino Cancer Care in Encino, CA. “There’s almost no case in which a patient shouldn’t be considered for a secondary [medication].” However, there are exceptions.
In doublet therapy, the most common approach, oncologists prescribe two drugs: an androgen deprivation therapy (ADT) drug, such as Lupron, with either the chemotherapy drug Taxotere (docetaxel) or one of the newer, more effective anti-androgens: Erleada (apalutamide), Nubeqa (darolutamide), Xtandi (enzalutamide), and Zytiga (abiraterone). Zytiga blocks testosterone production outside the testicles, while the other drugs prevent testosterone from binding to proteins called androgen receptors, which would otherwise stimulate prostate cancer growth. “For most patients with newly diagnosed metastatic prostate cancer, using Lupron with an [anti-androgen] or chemo is the standard,” says Dr. Vira.
A major shift in treatment has seen drugs like the newer anti-androgens used earlier in the disease. Dr. Vira says that they once were approved only for men whose prostate cancer had stopped responding to standard hormone therapy. Over the past several years, research has shown these drugs to be very effective when given earlier on, in combination with ADT. “One of the debates that happens all the time is about the right sequence of medications,” says Dr. Vira. Using them before cancer becomes castrate-resistant is a welcome development, says Dr. Liu: “We are pushing survival with these new treatment options.”
The hurricane moving up the coast is expected to bring muggy weather Friday followed by a cool-down and chance of showers over the weekend.LOS ANGELES, CA — The dramatic record-setting heatwave that's lasted for 10 days, spurred on wildfires and brought California to the brink of an energy crisis may come to an end every bit as dramatic as it started thanks to Hurricane Kay.The Hurricane making its way up the coast of Baja California is expected to bring thunderstorms and a chance of rain Friday through Monday along wit...
LOS ANGELES, CA — The dramatic record-setting heatwave that's lasted for 10 days, spurred on wildfires and brought California to the brink of an energy crisis may come to an end every bit as dramatic as it started thanks to Hurricane Kay.
The Hurricane making its way up the coast of Baja California is expected to bring thunderstorms and a chance of rain Friday through Monday along with a significant drop in temperatures, according to the National Weather Service. Despite the cloud cover and chance of rain, Friday is expected to be hot as well as muggy. The week-long excessive heat warning will remain in place through Friday. A cool-down won't start until the weekend, according to the National Weather Service.
Encino-Tarzana is expected to have a high of 100 degrees Friday and a chance of rain before cooling down to 84 degrees by Saturday, according to Accuweather. The chance of rain is highest Saturday and Sunday.
The weather service is predicting a 30 percent chance of lightning, thunder and showers, starting Friday, increasing to a 60 percent chance of rain by Saturday in Los Angeles County. With the unsettled weather, temperatures are expected to drop by more than 20 degrees across parts of the region.
The actual impact of the storm is still a little uncertain because it's unclear how much Kay will weaken as it moves north. But National Weather Service forecasters said the storm will bring clouds and chances of showers and thunderstorms in some areas.
The latest models predict the storm system may not move as far north as earlier predicted, but forecasters said Los Angeles County is still likely to see some rain.
The impact of Kay could be felt locally as early as Friday, according to the NWS, which noted that the storm will begin to push some cloud cover across the region. Absent those clouds, Friday was predicted to be the hottest of the next three days, "and it still might be even with the cloud cover," according to the NWS.
Excessive heat warnings will be in place in most of the Southland through Friday, with some possibly extending into Saturday morning, forecasters said.
Saturday is expected to start off warm, but depending on Kay's advance, temperatures should "level off quickly and possibly cool some during the day as showers develop," according to the NWS.
The amount of rain that will fall remains a mystery, but the NWS predicted "measurable precipitation" in the area.
"Widespread light to moderate rain is likely Saturday and maybe Sunday, mainly over Los Angeles and Ventura counties," forecasters said. "Isolated thunderstorms are also expected, especially in the mountains, which could produce heavy rain and flash flooding."
City News Service and Patch Staffer Paige Austin contributed to this report.
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