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Santa Monica, CA Experts in Container Rental, Sales & Customization

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Southwest Mobile Storage - Best Mobile Storage & Office Containers In Santa Monica, CA

Southwest Mobile Storage is a family-owned shipping container business founded in 1995. Our strength for more than 25 years comes from the specialized knowledge and passion of our people, along with serving over 24,000 commercial, construction and residential customers. Our facility and expertise in maintaining, manufacturing, and delivering corrugated steel containers is unrivaled in the industry.

While the rental side of our business is regional with branches throughout the Southwest, our container sales and modification operations are nationwide and becoming global. Santa Monica, CA offers a wide selection of portable offices and mobile storage containers you can rent, buy or modify.

Our experts in container rental, sales and customization are committed to providing you the highest quality and best experience from service to delivery - our reputation depends on it.

Whether your need is for storage, office space, moving, multi-purpose or custom use, we've got your back. Here's how:

Storage Containers Santa Monica, CA

NO MATTER YOUR NEED, WE'VE GOT YOUR BACK.

STORE AT YOUR LOCATION

We bring your storage container to you for convenient, easy access at your home, business or jobsite. Plus, you'll get more choice in storage space and better security, for a fraction of the cost of a pod or add on building, saving money and energy.

STORE AT OUR LOCATION

Not enough room to keep a storage container at your business, home or construction site? No problem - we can store it for you. Plus, you get 70% more space and better security, for a fraction of the cost of public storage units.

CUSTOM STORAGE

Need a permanent storage solution for your business, residence or construction? We sell new and used shipping containers in many sizes with a variety of add-ons. Or customize a container to your specific storage needs with our certified fabrication experts.

LOCAL MOVE

Take your time packing with our moving containers. We'll deliver to your business or home and pick it up whenever you're ready to move. So, you don't have to stress about moving or making multiple trips in one day, like if you rented a moving truck.

LONG-DISTANCE MOVE

Our moving container solutions ensure the long-distance move of your home or business is highly efficient and affordable throughout the southwest. In fact, we usually cost 20%-40% less than full-service movers.

MOVING & STORAGE

We understand move-in and move-out dates might be different. We can store your moving container at our highly secure facilities until you're ready to move to your new home or business location, and you can conveniently access it at any time.

OFFICE USE

Whether you need a workspace, conference room, or other office requirement, our ground-mounted mobile offices meet any and all of your business needs. Plus, it's faster and easier than building additions.

BUSINESS USE

If you need your shipping container to serve multiple uses, such as office-storage combos, breakrooms and even utilities, we've got you covered. We'll modify a custom container to fit your business needs and bring your business to the next level

CUSTOM USE

We'll create a custom container to fit your unique needs anywhere in the US. With our container modification expertise, we make any idea a reality. From pop-up stores to multi-story structures, our unrivaled facilities and fabrication experts do it all.

You'll get your own dedicated storage and container expert to serve as your one point of contact for easy, convenient service you can trust.
With our wide selection of intermodal containers for sale and rent, you'll find exactly what you need, from size, to type and condition.
We maintain our rental fleet to the highest standard - our integrity depends on it.
Our certified, experienced Conex container modification experts have more than 500 years combined experience modifying ISO containers.
All of our containers come with high security dual-locking system for no additional charge, so you can rest assured your stored items stay safe and that you don't have to pay extra for it.
icon-scale
At our unrivaled 90,000 sq ft indoor fabrication facility, ensuring your custom shipping container is made exactly to your specifications.
With our level of service, quality and expertise, you won't find a better value anywhere else.
Our portable offices include lighting and electrical outlets, internet hookups, HVAC and were crafted by our in-house steel container fabrication experts for top-quality construction.

Premium Quality - High Security

With Southwest Mobile Storage, you get much more than a POD or typical Conex box. You also get high security, unparalleled service and unmatched container modification expertise and facilities. No other company offers that much.

Shipping containers and storage containers come in a range of sizes. The most common external lengths are 20ft and 40ft with a width of 8ft. ISO Containers are typically 8ft 6in tall, but high cube containers are 9ft 6in tall. We also have steel containers in a variety of sizes from 10ft long to 45ft long to rent or buy, and we can modify shipping containers into any size you want.

 Rent Storage Containers Santa Monica, CA

SMS Mobile Storage Containers have these high quality features:

1/8" thick steel plate bottom side rails
High strength steel supporting cross members
1 1/8" thick hardwood floor with galvanized self-tapping screws
16-gauge corrugated steel walls
16-gauge roof
270-degree swing cargo door(s)
High security dual-locking system*
Spot-grinded, primed & repainted with a beige high-grade water reducible alkyd direct-to-metal enamel*
* Comes standard on all rental units

SMS portable workspace containers have these structural features:

High security window bars, lever & deadbolt set with lock box
Studs & R-19 Insulation covered with wood paneling
1 1/8" marine board floor is covered with a durable single part gray epoxy coating
Dual pane low-E horizontal sliding windows with screens and miniblinds
18 Gauge steel polystyrene core 3-hour fire rated personnel door
All of our workspaces are manufactured in-house and arrive new or restored to factory specifications
Exterior load center operating on 100 Amp single phase 230 Volt power
Light switch, receptacles and 4' light fixtures; all wiring is Romex 12/2
CAT-6 voice and data lines with electrical junction box
HVAC units ranging from 1 ton to 2 ton on rentals; ability to customize up to 10 tons of cooling

Having flexible storage containers options is important, but security is crucial to protect your peace of mind and your possessions.

At Southwest Mobile Storage, we don't believe in leaving things to chance. We want you to rest easy knowing your inventory, documents, tools, equipment and other items are safe 24/7. That is why we equip SMS high-security slide bolt locking systems and lockboxes on our entire fleet of rental freight containers.

EVERY ONE OF OUR MOBILE STORAGE CONTAINERS FOR RENT IN Santa Monica, CA, INCLUDES THE FOLLOWING SAFETY MEASURES:

High-security slide-bolt locking system and extra-long lock box, giving you twice the security and peace of mind.
No holes to ensure your rental shipping container is wind and water-tight.
No rust for your safety.
14-gauge corrugated steel for strength and reinforcement.

Contact us to speak with a helpful, friendly representative to better understand our full range of capabilities. We are happy to answer any questions you have, go over pricing and set up a time and place to deliver your Conex box. Our quotes are 100% free and you are under no obligation to pay for your consultation.

COMMERCIAL STORAGE CONTAINERS TO RENT, BUY OR MODIFY IN Santa Monica, CA

When you own a business or manage one, it's crucial to have efficient, affordable ways to store inventory and supplies, whether it's to grow your business or adapt to changes in the market, like the many caused by the pandemic.

Renting storage containers to keep at your business eliminates the cost and hassles of sending your staff to offsite storage facilities. Steel containers with roll up doors make storing and retrieving items faster and easier. Auto repair shops and other businesses that need easy access throughout the workday to secure storage for tools, parts, equipment or supplies find renting shipping containers to be the best solution for their business storage needs. Southwest Mobile Storage has your back.

 Storage Containers For Rent Santa Monica, CA

Renting portable offices gives your business more workspace, breakrooms, pop up stores, security booths and more, without the cost and red tape associated with constructing building additions. Plus, a steel storage container fits neatly into one parking space and provides much stronger security than Pods and way more convenience than self-storage units.

If you have a specific need, we can modify shipping containers to build whatever you need to grow your business. Whether it's a portable workspace to run your business, like a pop-up container bar, or a durable facility for scientific research, like a container laboratory, or even a container gym, our unrivaled fabrication facility and modification experts got you covered. Our full-time, in-house staff of certified welders, engineers, electricians, carpenters and painters have over 500 years combined experience modifying thousands of container projects for just about any business use you can imagine.

WHETHER YOUR BUSINESS IS COMMERCIAL, HEALTHCARE, GOVERNMENT OR EDUCATION, OR YOUR INTEREST IS TO RENT, BUY OR MODIFY SHIPPING CONTAINERS, SMS HAS YOU COVERED:

One
Offsite storage alternatives cause a mess of hassles and headaches. Expanding office space and storage capacity at your location saves time, money and hassle of making multiple trips offsite.
We offer more choice in security, size and features in steel Conex boxes or ISO shipping containers than a public storage unit or Pod for less cost and far greater service.
We offer flexible, month-to-month rental agreements and prorate by the day after your first 28-day billing cycle.
With us, you get a dedicated account manager you can rely on, so you can focus on running your business than waste time with a different person every time you call that doesn't know or care as much.
While other companies may have some staff for modifying containers, most outsource the work, so you don't know who is actually doing the modifications or how much they're marking up the price.
 Mobile Storage Containers Santa Monica, CA
When you modify a shipping container for your business, you won't have to worry about expensive, lengthy and complicated construction.
We have modified thousands of containers nationwide and internationally for more than 25 years for NASA, US Navy, GCP Applied Technologies, Helix and Sundt to name a few. And rent containers to Amazon, Walmart and many of other nationally recognized brands.
Our extensive staff makes it possible to custom build multiple projects simultaneously and our 90,000 sq ft indoor fabrication facility prevents contaminants from interfering with fabrication, which delivers better quality and precision.

CUSTOM CONTAINERS FOR YOUR HOME IN Santa Monica, CA

Building additions to your home can be very expensive and requires going through the hassle of securing permits and waiting for construction. You can save money, time and stress by modifying a shipping container instead. Whether you need additional space for a home gym, recreation or storage, we can convert steel containers into anything you can imagine. Our custom container gyms, man-caves or she-sheds, garages and more give you the extra space you need without the hassle, cost and wait that comes with home renovation.

Renting shipping containers for temporary storage, either when moving or dealing with restoration from a fire or flood, provides a secure, convenient way to keep your belongings close for accessing them whenever you need to. Plus, renting mobile storage containers for moving costs less than traditional movers and allows you to take your time packing, reducing the stress that comes from moving. You can also rent portable offices for your home to make working remotely distraction-free.

 Rent Shipping Containers Santa Monica, CA

HERE'S WHY YOU SHOULD CHOOSE US TO RENT, BUY OR MODIFY A SHIPPING CONTAINER FOR YOUR HOME:

With an extensive in-house staff and 90,000 sq ft container modification facility, we're able to deliver consistently high quality and work on multiple projects simultaneously for a fast turnaround.

Other companies don't have the facility, staff or resources to modify shipping containers and will outsource the work to various shops who may not have the special experience or tools needed to modify the right way.

You can rest assured knowing your custom container is safe in our hands. Our certified weld and quality control inspectors ensure everything is structurally sound and built to your specifications through every step of the process.

Renting a moving container from us makes your move much less stressful because you won't have to rush to pack your whole house into a moving truck in one day. Instead, you can take your time packing over the course of a month.

Our ISO shipping containers are weatherproof and come with vault-like security, so you don't have to worry about theft or damage to your belongings.

You won't get that level of security from U-Haul or other moving truck companies.

Renting a storage container at your home keeps your belongings close and gives you convenient 24/7 access, so you're always able to retrieve the contents of your container when you need to.

We know move in and move out dates don't always line up. We can store your packed rental container at our secure facility until your new home is ready.

With our mobile storage containers for rent in Santa Monica, CA, you can save up to 40% when compared to full-service long-distance movers, while gaining more flexibility in your schedule.

MOBILE STORAGE CONTAINERS & PORTABLE OFFICES TO RENT, BUY OR MODIFY IN Santa Monica, CA

We know your needs may change suddenly. With our extensive inventory and variety of sizes of portable offices and shipping containers to rent, buy or modify in Santa Monica, CA, we provide fast service and the best value possible so it's easy for you to get whatever you need when you need it.

Renting storage containers and portable offices from us gives you more flexibility when it comes to your schedule and options. If you don't have enough space at your current location or simply would prefer offsite storage, you can keep your rental storage and office containers at your location or ours - whichever is most convenient for you. You also get more options to choose from when it comes to size and features, like portable offices with divided rooms for private meetings or office/storage combos for storage and office space in one container. All while costing a fraction of the price of a pod or self-storage facility.

You can also buy new or used freight containers from us and choose from a variety of add-ons, including lights, electricity, doors and windows. Or fully customize a shipping container to save time, money and energy by skipping the expensive, lengthy process of constructing building additions. We can modify a Conex box into whatever you can imagine for any use you need, from construction tool cribs to office buildings, monitoring stations, mobile communication towers and much more. The possibilities are endless.

HERE'S HOW WE'VE GOT YOUR BACK:

You'll never face hidden fees or surprises with us. We give you transparent billing up front at the best prices.

With us, you get a reliable, dedicated point of contact, who keeps you updated every step of the way. You can rest assured knowing you'll always get what you need, when you need it.

No other company has the breadth and depth of staff and experience that we do when it comes to modifying shipping containers. Our certified welders, engineers, electricians, plumbers, carpenters and painters have more than 500 years of combined experience in fabricating custom steel containers.

We prorate your rent by the day after the first 28-day billing cycle, so you don't have to pay for a full month when you only have your mobile containers and offices for a few days.

While other companies may be able to do small container modifications, most don't have an in-house fabrication staff or 90,000 sq ft fabrication facility like we do. As a result, they outsource the work on your custom container, so you don't know who's actually building it.

Rest assured knowing your modified shipping container will be built to the highest quality standards. Our certified weld and quality control inspectors check every step of the fabrication process to ensure everything is structurally sound and built to your specifications.

HOW RENTING A STORAGE CONTAINER AND MOBILE OFFICE WORKS

Whether you're in need of a storage container for your commercial business, a portable office for your construction site, or a moving container for your home, our process is simple and straightforward.

Choose Your Container

Choose the mobile storage solution that works best for your needs. In this step, you will let us know the number of containers you need, their sizes and what types of doors to equip.

Choose Your Options

Let us know if you would like to add any of our rental options, like a folding table or shelving.

Choose Your Security

Choose from padlocks, puck locks and other enhanced security options. All of our storage containers come standard with dual-locking, vault-like security.

Choose Your Delivery Timeframe

You can expect standard delivery within 3-5 days of your order. If you need expedited delivery, we will do everything in our power to accommodate your needs.

Pick-Up Planning

Do you need to keep your shipping container at our location? Prefer to have our team deliver your packed container to a location of your choice? Let us know, and we'll be by your side to work out the logistics.

HOW RENTING A STORAGE CONTAINER AND MOBILE OFFICE WORKS

1

DETERMINE DESTINATION

Let our team know where we should deliver your mobile storage container for rent in Santa Monica, CA. Be sure to let us know if there are any special conditions that might prevent our drivers from entering your chosen destination. Before you schedule your delivery, let us know which direction you would like the doors of your container to face.

2

SCHEDULE DATE & TIME

Our drivers can deliver your storage container Monday-Friday, between the hours of 6AM and 2PM local time. Our two-hour delivery window is the most precise in the industry. If you desire another delivery time outside of our standard delivery options, we will do our best to accommodate your needs. As a courtesy, our driver will call you at least 30 minutes before they arrive at your drop-off destination.

3

PREPARE FOR YOUR MOBILE STORAGE CONTAINER DELIVERY

Before we deliver your Conex box, prepare your delivery area by ensuring that there are no low overhangs, arches, wires, trees or any other obstacles that could interfere with your delivery. It's a good idea to mark the space where you would like your steel container placed.

4

DELIVERY & SETUP

When our driver arrives, they will back our truck into the space where you would like your shipping container placed. Once we arrive, we will ensure that your container is delivered safely and securely. If placed on asphalt or pavement, we will use wood dunnage pads to make sure your ground surface is protected and the container is level.

HAVE QUESTIONS ABOUT MOBILE CONTAINERS TO Rent, Buy OR Modify IN Santa Monica, CA?

Check out our FAQ page or reach out to our helpful customer service team today @

909.341.4736

Latest News in Santa Monica, CA

Santa Monica Approves Ordinance To Limit Outdoor Watering

The city will limit outdoor water to two days per week along with other restrictions amid severe drought in the Southland.SANTA MONICA, CA — Santa Monica residents will soon be restricted to watering outdoors two days a week between 9 a.m and 5 p.m. amid the ongoing drought across the Golden State.On Wednesday night's meeting, the Santa Monica City Council approved the new restrictions under Santa Monica's Emergency Water Conservation Ordinance, which will take effect July 5.As the state continues to experience s...

The city will limit outdoor water to two days per week along with other restrictions amid severe drought in the Southland.

SANTA MONICA, CA — Santa Monica residents will soon be restricted to watering outdoors two days a week between 9 a.m and 5 p.m. amid the ongoing drought across the Golden State.

On Wednesday night's meeting, the Santa Monica City Council approved the new restrictions under Santa Monica's Emergency Water Conservation Ordinance, which will take effect July 5.

As the state continues to experience scorching temperatures, more frequent wildfires and a persistent drought, the ordinance is intended to help the city align with statewide conservation goals.

READ MORE: Mandatory CA Water Cuts Loom, 'Aggressive' Conservation Urged

Santa Monica residents currently use less than 80 gallons of water per person per day, according to a news release from the city. The July restrictions are expected to reduce the city's water demand between 5 to 13 percent or by 97 to 244 million gallons of water, over a six-month period.

"While Santa Monica has done an amazing job conserving water and decreasing our reliance on imported water, we need to do more locally to help secure our shared resource across the state and region," said Santa Monica Public Works Director Rick Valte. "By approving this new outdoor watering restriction, we not only align with neighboring water agencies, but we continue to lead the region on water conservation efforts."

As historic drought continues to grip Los Angeles County, LA City Attorney Mike Feuer urged Angelenos not to shoot off illegal fireworks this Fourth of July, noting the region's dry conditions that could cause any fire to spread quickly.

"All fireworks in the city are illegal for personal use and only professional and permitted firework shows are the places where Angelenos should go to celebrate the Fourth of July with a fireworks display," Feuer said.

He noted that in 2020, a Northridge apartment building, at 8651 N. Wilbur Ave., burned down due to Fourth of July fireworks.

"And of course, because of our drought, any fire that starts is going to spread very quickly," he said.

The Golden State continues to dry up under extraordinary drought conditions, and Gov. Gavin Newsom last month warned Californians to step up conservation efforts or face mandatory water restrictions.

"Every water agency across the state needs to take more aggressive actions to communicate about the drought emergency and implement conservation measures," Newsom said in a statement. "Californians made significant changes since the last drought but we have seen an uptick in water use, especially as we enter the summer months. We all have to be more thoughtful about how to make every drop count."

Even Wealthy Santa Monica Homeowners Qualify For Mortgage Relief Now

California just expanded a pandemic program to help homeowners who fell behind on their payments. See if you qualify. SANTA MONICA, CA — California expanded its mortgage relief program this month to offer support to those who are still falling behind on their payments as the COVID-19 pandemic drags on, officials announced.Most California families might be surprised to find out that they meet their county's income requirement for mortgage help. For Example, a family of four in San Francisco could earn $279,600 and still ...

California just expanded a pandemic program to help homeowners who fell behind on their payments. See if you qualify.

SANTA MONICA, CA — California expanded its mortgage relief program this month to offer support to those who are still falling behind on their payments as the COVID-19 pandemic drags on, officials announced.

Most California families might be surprised to find out that they meet their county's income requirement for mortgage help. For Example, a family of four in San Francisco could earn $279,600 and still be eligible for up to $80,000 in help. In Riverside County, the same family could earn $132,000 while In Orange County a family's household income could be as high as $203,250 to qualify.

For example, in Los Angeles County, for a household of five people, that area median income is $192,950. If an applicant's household income is at or below that amount, they may be eligible for funding.

In Santa Monica and anywhere across the state, residents can calculate their area's median income and enter their household size by using the program's AMI Calculator here.

In May, data showed that Santa Monica home prices have not gone up since last year, according to Redfin. Houses were selling for a median price of $1.6 million. There were 69 homes old in Santa Monica in May this year, down from 88 last year, Redfin reported.

The program was amended to include homeowners who missed payments in the first half of 2022. It also expanded its income eligibility and will now cover past-due property taxes for a wider group of homeowners, according to a news release from the program.

Homeowners who miss at least two payments before June 30 may now be eligible for full reimbursement for missed housing payments for up to $80,000, officials said. Before this change, homeowners had to have missed at least two payments before the program's launch on Dec. 27, 2021.

"Many California homeowners, like many renters, felt the impact of COVID-19 on their household finances, putting them at risk of losing the homes they've worked so hard for," said Lourdes Castro Ramírez, Secretary of the California Business, Consumer Services and Housing Agency in a release.

What's more, funding for past-due property taxes will extend to mortgage-free homeowners and those whose mortgage payments are current, according to the program. Newly eligible homeowners could receive up to $20,000 to cover past-due property taxes if they missed at least one payment before May 31.

Since the program first launched, more than $68 million has been distributed to some 1,900 California homeowners struggling from the economic fallout spurred by the pandemic.

There's currently no deadline for applications, but homeowners in need are urged to apply as soon as possible at CaMortgageRelief.org. The program can also be contacted at 1-888-840-2594.

Amazon, Kong Studios Opening Offices In Santa Monica

SANTA MONICA, CA — Amazon and game developer Kong Studios Inc. are adding new offices in Santa Monica, city officials announced this week.The move is happening during a significant growth period for both companies, city officials said.And it's a good sign for the city, with officials expecting the move to bolster the local workforce and add even more technology, game dev...

SANTA MONICA, CA — Amazon and game developer Kong Studios Inc. are adding new offices in Santa Monica, city officials announced this week.

The move is happening during a significant growth period for both companies, city officials said.

And it's a good sign for the city, with officials expecting the move to bolster the local workforce and add even more technology, game development and corporate job opportunities to the region.

"The expansion of Amazon and Kong Studios are welcome additions for job creation and a promising sign for our city's economic growth," Santa Monica's Economic Development Manager Jennifer Taylor said in a statement.

More businesses coming to the city is a good sign for the city, which took a hard economic hit in the pandemic.

Interested in local real estate?Subscribe to Patch's new newsletter to be the first to know about open houses, new listings and more.

"As we navigate the lasting impacts of the pandemic, economic recovery remains a priority for the city, and we're pleased to see these positive trends in new business activity that build on our talented local workforce," Taylor said.

Amazon will open a new "tech hub" in Santa Monica as part of the company's growing presence in Southern California, which also includes plans to lease office space in Irvine and San Diego.

The new location is slated to open in mid-2023. The new Santa Monica site is the company's largest lease in the region and will bring more than 1,000 new tech and corporate jobs to Santa Monica alone.

Amazon has signed a deal to rent a 200,000-square-foot space at the Water Garden business center. The complex already houses an office for Amazon Studios.

This spring, U.S. game developer Kong Studios Inc. announced plans to relocate its headquarters from Nevada to Santa Monica. With the move, Kong Studios aims to increase the creation of its next high-profile game, and expand its Intellectual Property and the role of its headquarters.

Technology and innovation remain one of Santa Monica's leading economic sectors, currently employing more than 29,000 people with an average quarterly payroll of $1.95 billion. The city is already a hub for notable tech companies, including Snap, Inc., Hulu, Headspace, GoodRX and Oracle and game development companies such as Naughty Dog.

"The added presence of Amazon and Kong Studios is a testament to Santa Monica's technology sector and its robust and diversified local economy," city officials said.

New cancer vaccine finds way to overcome tumor defenses

Developing cancer vaccines have been an essential part of cancer research for almost three decades.Many forms of cancer vaccines are under research, including those that target proteins expressed across multiple cancer types, and those that are perso...

Developing cancer vaccines have been an essential part of cancer research for almost three decades.

Many forms of cancer vaccines are under research, including those that target proteins expressed across multiple cancer types, and those that are personalized according to individual tumor mutations.

While existing vaccines can induce an immune response in blood, tumors often dodge this response via an immune escape mechanism.

Targeting this mechanism may help researchers improve cancer vaccine efficacy.

In a recent study, researchers developed a new cancer vaccine that targets this immune escape mechanism and increases immune antibody levels.

Dr. Santosh Kesari, director of neuro-oncology at Providence Saint John’s Health Center, chair of the Department of Translational Neurosciences and Neurotherapeutics at Saint John’s Cancer Institute in Santa Monica, CA, and regional medical director for the Research Clinical Institute of Providence Southern California, who was not involved in the study, explained to Medical News Today how the vaccine worked.

“This new approach [t]argets this resistance mechanism by making a vaccine to a general protein that is over expressed (a stress signal) in cancers but is rapidly removed by the cancer before the immune system detects it.”— Dr. Santosh Kesari

“The new vaccine approach prevents the cancer cell from removing this cancer-specific protein and thus allows a coordinated immune attack on the cancer by both T- cells and natural killer (NK) cells,” he said.

The researchers designed the new vaccine to target MICA and MICB stress proteins, which sit on the surface of cancer cells.

While immune cells in the body, known as T cells and NK cells, typically bind to these stress proteins in an attempt to kill cancerous cells, tumor cells can evade their attack by slicing MICA/B and shedding them.

The new vaccine prevents this slicing and thus increases stress protein expression and the activation of a dual attack from T cells and NK cells.

To begin, the researchers administered their new vaccine to mouse models of cancer that were modified to express human MICA/B proteins.

They found that the vaccines increased antibody levels in the mice, and demonstrated anti-tumor effects.

The researchers then evaluated immunological memory from the vaccine. Four months after initial immunization, the researchers exposed mice to tumor cells and found that they remained fully protected.

The researchers also found that introducing small quantities of blood from vaccinated mice inhibited cell-surface MICA/B protein shedding on human and mouse cancer cell lines.

The researchers further noted that the vaccine was effective in controlling multiple tumor types.

The researchers next investigated whether the vaccine could prevent cancer recurrence following surgical tumor removal.

To do so, they immunized mouse models of breast cancer and melanoma with a high chance of recurrence after tumor removal with either the new vaccine or a control vaccine.

They found that, compared to the control vaccine, the new vaccine reduced the number of lung metastases detected in both cancer models more than a month after surgery.

The researchers next tested the vaccine on four rhesus macaques (commonly known as rhesus monkeys). They noted that the vaccine increased antibody levels by 100- 1,000 fold with subsequent booster vaccines.

They reported no clinical side effects or changes in blood chemistry following immunization, which, they wrote, suggests preliminary evidence for vaccine safety.

The researchers concluded that their new vaccine enables protective immunity against tumors with common escape mutations.

The researchers noted that their results might be limited as they had to express human MICA/B proteins in mouse tumor cells due to differences in mouse and human cellular biology.

When asked what the future holds for research around the vaccine, Dr. Kai W. Wucherpfennig, chair of cancer immunology and virology at the Dana-Farber Cancer Institute and lead author of the study, told MNT that they plan to enter the vaccine into clinical trials next year.

The researchers added that the vaccine might also be used in combination with local radiation therapy as DNA damage enhances MICA/B expression by cancer cells.

“Since this is a broad target to general cancer stress signal, the vaccine may have broad applicability to many cancers and thus could be made to be an off-the-shelf approach,” Dr. Kesari added.

Although the study presents an exciting new approach to cancer vaccines, the results remain preclinical, noted Dr. Kesari.

“[Thus it] will need to be translated in the future in humans by conducting phase I clinical trials in the future to prove out its safety and efficacy,” he concluded.

Classic Santa Monica Restaurant Izzy’s Deli Has Closed Permanently

Izzy’s Delicatessen in Santa Monica, located on the corner of 15th and Wilshire, and one of the last remaining Jewish delis in the seaside city, has closed for good, reports the Santa Monica Observer. The former 24/7 restaurant now has “For Lease” signs posted, with a real estate agent confirming to the Observer that the space is up for $25,000 a month. Shuttered since November 2020 to undergo re...

Izzy’s Delicatessen in Santa Monica, located on the corner of 15th and Wilshire, and one of the last remaining Jewish delis in the seaside city, has closed for good, reports the Santa Monica Observer. The former 24/7 restaurant now has “For Lease” signs posted, with a real estate agent confirming to the Observer that the space is up for $25,000 a month. Shuttered since November 2020 to undergo renovations, Izzy’s promised customers with signs strewn across the front that it would reopen in June.

Without any substantial outdoor space, plus pressure from delivery apps, the deli found it difficult to navigate through all the changes during the ongoing pandemic. Owner Izzy Freeman opened the deli in 1973 with Kenny Horowitz. Izzy’s was a classic Jewish deli with pastrami sandwiches, knishes, and other all-day classics. Freeman announced that though he had every intention of reopening, he has decided to retire. Inside there were numerous photos of famous people who had frequented the restaurant over the years.

Izzy Freeman, the so-called “Deli Lama,” gave the following statement regarding the closure:

After 47 amazing years of serving the community 24/7, 365, the time has come for Izzy’s Deli to officially close its doors. We had every intention to reopen post-pandemic but it has become apparent that the only option at this point is to retire.

I’d like to thank my incredibly loyal customers who became friends, the three generations of my family who called IZZY’S their second home, and the two generations of employees who made IZZY’S DELI a landmark in Santa Monica.

Over the years we became ingrained in our customers’ lives — we saw first dates that became engagements, husbands awaiting the births of their children who eventually came in as parents themselves, customers becoming friends with each other, families gathering year after year after year, late night study breaks, business meetings, holidays and just enjoying each and every day. We laughed, we loved, we cheered, and boy did we EAT!!

Our matzoh ball soup, overstuffed sandwiches, tuna melts, and Thanksgiving dinners brought in customers from just around the corner, thousands of miles away and everywhere in between. Together, we truly made my childhood dream a reality and brought a taste of New York to Santa Monica, and for that, I will be forever grateful.

Thank you, from the bottom of my heart, for 47 wonderful years! This may be the end of this road, but it’s certainly not goodbye.

Izzy

Boasting a new separate bar menu with entree-sized plates, Camphor has some choice new dishes from chefs Max Boonthanakit and Lijo George. Available at the restaurant’s 10 bar seats or outside on the patio, the menu features classic French bistro fare like lamb cassoulet, steak frites, stuffed rigatoni, trout almondine, Nicoise salad, and A5 wagyu croque monsieur. Prices range from $30 to $60 but are sized enough for one person to have as their main dish, a contrast from Camphor’s full menu, which tends to be more delicately sized for variety and sharing.

What Now LA has spotted a license change at Silver Lake Wine’s Arts District space. While part of the space will remain a wine shop, Silver Lake Wine partner April Langford confirms the liquor store will convert to a bar and lounge with potential live entertainment and dancing, with a 2 a.m. closure. The new venue adds to an increasingly crowded block, with Guerrilla Tacos, Lokels Only, and the upcoming Yess Aquatic.

Gong cha, which has seven stores in the LA area, is donating a dollar for every purchase of the boba shop’s rainbow strawberry taro milk tea to It Gets Better, National Queer Asian Pacific Islander Alliance, and the Trevor Project. The promotion goes through all of June to celebrate Pride month.

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Izzy's Deli

1433 Wilshire Boulevard, , CA 90403 (310) 394-1131 Visit Website

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